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SSX2 anticorps

Cet anticorps anti-SSX2 est un anticorps Lapin Polyclonal détectant SSX2 dans IF. Adapté pour Humain, Souris et Rat.
N° du produit ABIN6568037

Aperçu rapide pour SSX2 anticorps (ABIN6568037)

Antigène

Voir toutes SSX2 Anticorps
SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Reactivité

Humain, Souris, Rat

Hôte

  • 42
  • 6
Lapin

Clonalité

  • 45
  • 3
Polyclonal

Conjugué

  • 20
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SSX2 est non-conjugé

Application

  • 33
  • 13
  • 13
  • 9
  • 5
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
Immunofluorescence (IF)
  • Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human SSX2 (NP_783629.1).

    Isotype

    IgG
  • Indications d'application

    IF 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

    Autre désignation

    SSX2

    Sujet

    The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X,18)(p11.2,q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.

    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 21kDa/25kDa

    ID gène

    6757

    UniProt

    Q16385
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